But flying in the L or R seat is not all that different
I don't know about you, but sitting in the other seat, rather than automatically being able to lay your hand on a particular switch etc I had to stop and think about it and eyeball where in space the desired item resided.
A rather extreme example was an F-16 instructor being checked out in a PA-28, on approaching touchdown the instructor called for a go around. The F-16 chap pushed forward with his left hand and pulled back with his right as he would in his fighter, would have been OK had he been sat in the right seat, but not the left where he was.