Flybe former routes ex Southampton
Besides the former Flybe routes ex Southampton the airport has seen several other airlines and routes disappear over the course of the last decade or two including the following scheduled airlines and destinations.
Aer Lingus...Cork
Air Berlin... Paderborn
Air France... Paris CDG, Paris Orly
BMI Regional... Munich
KLM... Amsterdam
VLM... Antwerp, Brussels
Volotea... Ibiza, Palma
Vueling... Barcelona
I haven't included the former British Airways City Flyer destinations as they were replaced by Flybe.
Plus in the past Southampton Airport had the IT charters to the following destinations operated by the likes of Air Europa, Air Malta, BH Air, Euro Atlantic Airways, Iberoworld, Oasis, Spanair, Transeuropa, TUI (Britannia Airways and Thomson), Volotea.
Alicante
Faro
Ibiza
Malaga
Malta
Menorca
Palma
Tenerife
Varna
It's amazing really that Southampton Airport have certainly lost alot of airlines and destinations over the years.