Hi - two things come to mind ...
#1 They want people who can be promptly promoted to multi-crew command (required ATPL licence), without worrying about their "academic" abilities. This might apply to any airline type operators.
#2 It's an easy way to reduce the number of CVs. No one really wants to choose the "best" candidate - they just want a convenient number of adequate candidate!
If you're looking at airline work - time to get out the books! If it's single-pilot work, I'd say apply anyway, with a polite explanation.