Court Line certainly did 4, but the routes were shorter then, like the nearer Med rather than today's medium hauls like Cyprus and Egypt
...and I distinctly remember four "waves" at Luton in 1970 - 0800, 1400, 2000, 0200 when the whole fleet (8 aircraft) would arrive and depart within a couple of hours. As
Rog747 says, the sectors were short - GRO, PMI, IBZ, MAH, REU, RMI, GOA, ALC, and the aircraft were smaller (89/119 pax). Record turn-round in 1970 was IIRC 29 minutes, full load in, full load out.