In any aircraft with paired engines, it has to be an assumption that the catestrophic failure of one engine would be likely to lead to the failure of the adjescant one. Of the two types I have flown with paired engines, we used that assumption and trained for it regularly - it was a tricky situation but one that was surviveable if the correct techniques were applied.
One of these was the VC10, which was originally certified for this situation. It happened to BOAC twice to my knowledge, both times the aircraft landed safely.
The DEFATO (Double Engine Failure After Take Off) drill in the VC10 sim was one of the most demanding things I have ever done, but regular practice was necessary IMHO.