Nope.
For the B747-300 I think there was a "half flow" option on the pack controllers for use in crz. SOP's mandated what pack selection was used and 1 pack was not one of them. Personally I, FEO, only ever used half pack on the Capt direct instructions coz it saved 3/5 of 5/8 of FA fuel. The possible fuel savings disappeared in the static like heavy airframes - OJU was heavy and always had difficulties BKK-FCO while other aircraft made it OK.