Large (old) piston twins of yesteryear (Convair 440, Martin 404) used autofeather to ENSURE that the windmilling propellor was feathered. Even these aircraft would NOT climb if the prop was not feathered at high weights, and if autofeather was inop, the MTOW was reduced by a large factor.
These aircraft were certified to CAR4b (now FAR25)and generally had good engine out performance. Most light piston twins, sadly, do not.
Now, if you have turboprops (Cessna 441 is a good example), the picture changes greatly.