Samsonite, Delsey or Antler. Spares such as wheels and handles are available at any repair shop in the world when needed down route. They are strong and durable, won’t embarrass you when checking into a good hotel yet aren’t so flash they attract thieves like the Tumi aluminium ones. They’re the Toyota’s of the luggage world.
PacSafe make some good soft kit with anti theft features but aren’t designed to be repaired. I had to take mine into a repair shop to change the wheels which had to be drilled out. I could easily do wheels on a old Delsey myself with just a screwdriver.