ULH is making Emirates B777 Pilots leave in droves, they can only stand it for so long. Most Pilots who have been doing LH for many years look at least 10 years older than their actual age and will probably be dead in their late 60s. Having a successful career and getting a wide body command at an early age can be very bad for your health. At least the QF Pilots live at home and are protected by employment legislation and unions, unlike the EK crews.
The health implications of ULH need investigating in greater depth, this would undoubtedly result in recommendations for strict cut backs well below current limitations, possibly even only allowing a few years of ULH flying. This might not suit the Pacific Barons or the company but other occupations with a toxic or dangerous environment are heavily regulated.