The thing is even the “good little regional” model was marginal at best...MAN was tried and it was a disaster, BHD was tried and it was less than half full, EDI did OK but loads were far from spectacular and it was dropped, AMS was tried and loads were mediocre. Weekly to JER did OK. Med flights were tried and they were marginal at best.
I’m sure KLM could make a go of it a couple of times a day, BE could make another go of it with EDI, Ryanair could come in 4-5 weekly to some Med destinations. There is a bit of a market for bizjets and some freight. The problem is for the cost of reactivating the place it would be impossible to make any return, and any airline coming in would need considerable incentives to do so.