Absolutely!
Just look at how many incidents of a serious nature that have occurred recently in CX where fatigue has played a major part. Initially it may not be obvious and so it can easily be dismissed but it is insidious and potentially disastrous. Now put that into the equation with the continual decease in experience and there IS going to be a bad outcome. It is only a matter of time. Those that have been here a while are getting huge pressures when operating because of events that happen and insufficient backup from the other crew/s as they only have 'book' knowledge, no actual experience.
There have been aircraft divert under emergency conditions (suspected fire onboard) to an offline port then 'self certify' themselves and the aircraft as fit and depart.
There have been aircraft depart home base to be told enroute via acars that vital parts of the flight controls have not been refitted after maintenance and are still in the workshop.
There has been an emergency declared and diversion to a difficult airport while the CN was taking his inflight rest. Relief crew didn't wake the CN as that would prevent the flight meeting the requirement
of the FTLs. WTF!! If you are diverting and landing many hours short of destination then it is going to be irrelevant but thats what the inexperienced do, no common sense/practical application. Subsequently management had to recover the aircraft in unfamiliar and onerous conditions. They are management, don't have as much experience as the line pilots. They stuffed it up, destroyed an engine that those of us that had the experience of operating in this type of severe weather knew about but were sidelined.
There have been new aircraft types with problems but despite those problems becoming well known to management, operating crews where kept in the dark. Resulted in a serious incident where not only lack of readily available info being withheld from operating crew but engineering hiding behind an MEL that was not at all appropriate. Outcome? Discipline the crew where in reality the CN did an outstanding job in protecting the aircraft with absolutely NO support from management or engineering.
Right, now, tie this all together...try doing it when exhausted and you get crap decisions which when you are making them may seem logical but in the cool light of day, after getting well rested you question 'why did I do that?'.
In summary, the pressures exerted by fatigue when you need to be alert and clear thinking are increasing and though it's not the 'In' phrase anymore, the holes in the swiss cheese are going to line up and Bingo!!
I've only covered a very, very few of the recent events but it gives an idea of the trend and it is not good.
I don't want to revisit this post in the future and say the accident was forecast but that is exactly where CX is headed.