I said that if you enriched the mixture to around 25C ROP, you could move to thrash or punish territory. It is certainly the worst place to set the mixture if you're interested in engine longevity.
It's where the engine designers designed the engine to run! What evidence do you have that this affects engine longevity, assuming you observe the other engine limits e.g. CHT?
I suggest you do not attach a data logger to your car. It will do your head in to see what mixtures it runs, and when you are most likely to see knock detected.