When I was a freshly minted CPL (at the ripe old age of 24), unless you had at least 2,500 hours and a thousand multi by 25, you were NEVER going to be accepted by a major Domestic carrier!
And yet not so long ago, around the time Ansett went bust, 2,500 hours was no where near enough to even get a look in at flying a Chieftain with a charter mob...