Hokulea, I suspect it is saying that as AA is unable, at this time, to confirm all of your sectors. Perhaps it is the ITO-HNL, operated by HA, or perhaps one of their own flights, or one of the other code share sectors.
It is something the computer system cannot resolve on its own, a human has to look at it. Your PNR is likely queued to a human who will, eventually, get to it.
Difficult to speculate what the issue is but it could mean you taking a slightly longer connection (if it is HNL-ITO) or perhaps fly on another day. Talking to a human is your best solution, particularly if you have yourself done some analysis? i.e. Ask yourself if it is the HNL-ITO that is a problem, which subsequent flight would I want. Same if it is the LAX-LHR. Knowing what options you would choose, in advance, can expedite the process, once you find a human to talk to.