Simulators are generally very restricted in what can be practiced in terms of disorientation – leading to LOC.
One good demonstration is to simulate IMC and apply a small out of trim condition, preferably with autopilot engaged, before getting the crew to disengage the autos.
The objective is to experience how difficult it might be to disregard some sense inputs (feel) and concentrate on the aircraft instruments. In some LOC events the body senses, particularly acceleration can be very disorienting.
Out-of-trim in roll is very effective (disturbing) – e.g. mishandled lateral fuel balance, but note the number of incidents – stall etc which have involved pitch trim.

bburks – see PM