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Drugs (legal) side effects.

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Drugs (legal) side effects.

Old 18th Apr 2021, 00:46
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Drugs (legal) side effects.

I've been lucky enough never to have medication for any length of time, anti-malarials and usual vaccines aside, but the Doc put me on Corticosteroids for urticaria (I'm no medic, but it's a broad term for raised skin rashes, which may look like chickenpox or measles, but in the absence of other symptoms they can be discounted).
A week on antihistamines had no effect, so I was invited to the surgery for a masked face to face with the Doc.

​​​​​​"Undress please".Look, poke, prod, squeeze, etc.
"Steroids, we don't like to use them as rule, but you need them."

Questions, answers, questions, answers from both sides followed.

Two days in, no adverse effects at all - four days in, and I don't even feel like sleeping. Calling the Doc again on Monday! Any such experiences please? Mods please move if necessary. Thank you.

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Old 18th Apr 2021, 08:32
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Usually you shouldn't be prescribed corticosteroids (like Prednisone) for a long period because they can become addictive ... and often require tapering off as part of the prescribed dose ... but the phrase 'like a xxxxx on steroids' does hold true ... you can feel that you are firing on all cylinders and moving mountains whilst you are on them! (Speaking from personal experience from past prescriptions!)
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Old 18th Apr 2021, 08:43
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and often require tapering off as part of the prescribed dose
My mum was permanently on steroids towards the end of her life - she suddenly started exhibiting some strange behaviour or symptoms (I can't recall now) so I phoned the Doctor and halfway through the conversation, metaphorically smacked my forehead and said "hang on, I bet she's stopped taking her steroids!" - Doctor said "I was just about to suggest that!". For some reason she unilaterally decided she didn't need them any more - 24hrs later, back to normal.
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Old 18th Apr 2021, 10:05
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One known side effect of a prolonged period of Prednisalone (UK name) is cataracts. I was on it for 4 years after having minimal change kidney disease that got me 28 days in hospital and 7 months off work....Fortunately, I had BUPA as part of my employment, and they paid over £5,000. That made an enormous difference…. In 2019, I was taken off Warfarin and moved to Apixaban: in January 2020, I was diagnosed with severe anaemia. Neither of the two GPS I saw at the practice were aware that the patient information leaflet for Apixaban said that 1 in 10 patients developed anaemia when taking it! So I had a lot of blood tests and iron tablets and then changed to Edoxaban which has the same warning, but so far seems OK. Currently on 11 tablets and two injections a day for the various ailments, and need something else for Benign Essential Tremors. The thing that works well, and was approved by the Geriatric Registrar (Excellent young lady! - she said alcohol would have that effect on BET and she was going to try it as an aperitif) is 1/3 gin, 1/3 dry vermouth, 1/3 tonic water, 2 ice cubes, a squeeze of lime juice and half a dozen drops of Angostura. But it does prevent driving.....
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Old 18th Apr 2021, 13:51
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I have had long experience of steroids since I was 14 years old,and at one time,for several years I was prescribed them as "PRM",ie patient requested medication,which meant that,essentially,I was self-prescribing,whenever I felt they were required.They can be very effective,and work when nothing else will,but should be taken at the lowest effective dose,for the shortest possible time.Apart from the benefits,I have experienced the side effects described above,the "steroid high".TLDNMCL,depending on the dose you are taking,you will probably find that after a week or two,you may start to put on weight,because they cause the body to hold water,and this is particularly noticeable on the face,where you gain a kind of chipmunk appearance -this is known as "Cushings syndrome".The skin also becomes sensitive to sunlight,and can become quite sore,so on sunny days,wear a wide-brimmed hat,and cover your arms.As Alsacienne says,if taken for more than a few days,they should be tapered off and not stopped abruptly,as they affect adrenaline produced by the body in the event of injury etc.While taking them,you should carry a steroid card,lest you have an accident etc,and are taken into hospital
Apart from the cataracts which may ensue,I think there are other possible eye problems,including euvitis (spelling ?) which I have had - v.painful,and one of the well known and common long-term effects is osteoperosis or brittle-bone disease,my late neighbour suffered terribly from this,after taking prednisolone ( only 5mg daily) for 60 years for asthma.She was a hunchback,and liable to break a bone with the slightest knock.
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Old 18th Apr 2021, 16:11
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Thank you all, I did a fair bit of reading up on this, but remained curious about personal experiences, hence the original post. Due to finish preds tomorrow, therefore will call the Doc first thing for dose reduction / full stop advice, but have a planned further two weeks on Fexofenadine.

Thanks again for sharing your experiences.
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Old 18th Apr 2021, 21:44
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Guess it was 7 years ago that prednisolone gave me instant relief from polymyalgia. Been on it ever since, but now tapered down to 2mg/d.
I reckoned it gave me a voracious appetite, and FType says I'm 10 months pregnant.
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Old 19th Apr 2021, 00:31
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The biggest problem with drugs is the side effects..
may cause flatulency, hair loss, tiredness, lack of sex drive, weight gain, muscle loss, etc etc etc.

you Never get may cause hair rejuvenation, increase stamina, increased sex drive, weight loss, muscle gain, increased penis length.. etc etc etc...

it’s about time they sorted out the side effects
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Old 19th Apr 2021, 13:37
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They have sorted the 'lack of sex drive' bit - the doc may (!) prescribe a well known enhancer for those who experience brewer's droop as a result of taking certain hypertension medication.
Just saying
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Old 19th Apr 2021, 21:22
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Originally Posted by NutLoose View Post
The biggest problem with drugs is the side effects..
may cause flatulency, hair loss, tiredness, lack of sex drive, weight gain, muscle loss, etc etc etc.

you Never get may cause hair rejuvenation, increase stamina, increased sex drive, weight loss, muscle gain, increased penis length.. etc etc etc...

itís about time they sorted out the side effects
I'm reminded of an acquaintance who finished his clown act by passing round the hat:
"More people die of Natural Causes than any other known disease. I'm collecting to stamp out Natural Causes"
And I heard one little old lady in the front row say to another little old lady "What a good idea."
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Old 19th Apr 2021, 21:48
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Talking

Originally Posted by NutLoose View Post

you Never get may cause increased sex drive, weight loss, muscle gain, increased penis length.. etc etc etc...

it’s about time they sorted out the side effects
Viagra was originally a heart drug, but apparently not very effective, then doctors noticed that numerous male patients were very reluctant to stop the treatment.
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Old 19th Apr 2021, 22:36
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Friendly word of caution. If you are taking Iron Supplements, it would be wise to abstain from taking any Male Enhancement medication; Viagra and such.

One of the side effects by taking both is that you may wind up standing outside for up to four hours pointing North.
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Old 19th Apr 2021, 23:02
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Originally Posted by 11Fan View Post
Friendly word of caution. If you are taking Iron Supplements, it would be wise to abstain from taking any Male Enhancement medication; Viagra and such.

One of the side effects by taking both is that you may wind up standing outside for up to four hours pointing North.
Damn! I was looking forward to a pint or two of Guinness in the pub garden. Would it take deviation and variation into account, or would I have to settle for a rough magnetic? I'd settle for rough these days to be honest...
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Old 20th Apr 2021, 03:55
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Brings a whole new meaning to "moral compass"...
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