The Canaries are an interesting proposition because of their location. Their population is over 2 million, with the island of Tenerife alone at approximately 1 million full time residents, although a good few of these are retired British, Germans and Spanish on full time holiday already. Las Palmas and Santa Cruz are sizable urban areas in their own right. It is worth remembering that this is not a high wage region of Spain. The financial crisis hurt the Canaries economy, which benefited enormously at the time from the construction boom.
As others have mentioned, there are many in the Canaries with Latin Amarican links, particularly to Venezuela and Cuba, but can people from these countries afford a trip East across the ocean enough to support the route?
Northern state based Americans could visit, but they don't need to visit. Florida, California, The Caribbean and Mexico are on their doorstep.
Brazil is a fast emerging market (albeit Portuguese in heritage), how long would a flight to Recife take?