I haven't seen anyone ask, or say, what the typical mission will be? Long distances and high altitudes make pressurization a very useful feature. The Seneca will likely cost half or third as much to purchase, and fit in a smaller hangar. The cost to overhaul a PT6 would buy a complete Seneca III.
I've had two loss of power events, both in twins. Not a scratch on me or aircraft. But a twin is not for the "casual" pilot.