Why is this so stupid a question?
For very obvious reasons !
As Capetonian hinted at, there are a million and one other safety factors to take into account when selecting an airline to fly with. The route the airline takes is only the tip of the iceberg.
Also, routing can be changed on a day by day, hour by hour basis, and as SLF there is bugger all you can do about it.... whatever information you may have made your route decision on may well have changed by the time you are strapped into your seat and at 30,000ft !
So what of the airlines that are still flying over Syria, Iraq and Afghanistan??
Or indeed what of the airlines flying into Israel ? Which airline would you pick JammedStab ?