HTB, I would suggest that in terms of operating crew comparing Reaper et al to future drones is much like comparing a B-36 to a B-2. One major purpose of the Taranis project, for example, is to vastly increase the automation of operation. Whether it will be politically acceptable to have a drone 'think' for itself is another question. There will, for Air to Ground missions at least, almost certainly be a ground operator - but only to permit/deny weapons release. Command of the airframe during any phase of flight will be by black box, not some chap or chapess dressed in a flying suit and sat in an iso-container.
I agree the support crew for an autonomous drone will be much as it is for a current type with a similar mission, but they tend to be much cheaper to train and keep than the '2-wing master race'.