From the airline's own website page at
MH370 Flight Incident | Malaysia Airlines
Saturday, March 08, 07:30 AM MYT +0800 Media Statement - MH370 Incident released at 7.24am
Sepang, 8 March 2014: Malaysia Airlines confirms that flight MH370 has lost contact with Subang Air Traffic Control at 2.40am, today (8 March 2014).
Flight MH370, operated on the B777-200 aircraft, departed Kuala Lumpur at 12.41am on 8 March 2014. MH370 was expected to land in Beijing at 6.30am the same day. The flight was carrying a total number of 227 passengers (including 2 infants), 12 crew members.
Malaysia Airlines is currently working with the authorities who have activated their Search and Rescue team to locate the aircraft.
The airline will provide regular updates on the situation. Meanwhile, the public may contact +603 7884 1234 for further info.