Israel were not too unhappy with the Assads running Syria, the family provided little trouble for decades.
The revolutionaries contain many salafists (including lots of volunteers from abroad, including the UK). Israel doesn't want these people running a country on their borders.
So to strike against Assad means they have a bigger problem. Or several.
Syria has Fateh-110 missiles from Iran, these are accurate super Scuds with a 200 mile range. Syria also has a substantial chemical weapons capability. Both of these give Israel sleepless nights. Especially if Syria supply Hezbollah with the missiles. Or just about anyone with the chemical weapons.
Jamraya is a collection of military complexes that are behind a mountain to the west of Baghdad, not a long way from the Lebanese border. This is the second time Israel has hit it. But this time they went in much bigger and took out an assortment of targets. Including using earth penetrators against the many bunkers there. That they succeeded to some degree in their aims can be seen with the immense firework display visible from Baghdad, which could well have been Fateh-110 solid fuel going up.
It looks like the West is planning a safe zone in the north, next to the Turkish border, which would then be declared as a no fly zone. This would help stem the refugee problem and give the West a vehicle to control the political process amongst the Syrian opposition, minimising salafist power. Expect Typhoons to be flying out of Akrotiri to enforce this.