Seven years ago at age 60 my Doc said that due to reaching that age I had moved into a higher risk category and he prescribed daily 40mg statins and 75mg aspirin. Very soon I experienced increased night cramps in my legs and the statin dose was reduced to 20mg which I have remained on with no ill effects. My cholesterol has reduced from 5.9 to 3.3.
After five years on the aspirin I began to feel ill with no appetite, was very lethargic and I lost 30lbs in weight over three months without trying. An endoscopy showed gastritis and duodenitis. I stopped taking the aspirin and have fully recovered. I gather that if you are going to get problems with aspirin it usually happens earlier in the course than it did with me.