No, loosing a HYD SYS on an a340 would, ad definitionam, of course not be an ETOPS problems. ETOPS refers to TWINS, hence the meaning of ETOPS!
Well, actually, FAA ETOPS now applies to four (and three) engine aircraft over 180 minutes from an airport. It's been in effect for almost five years now, with a one year grace period.
See:
AERO - The New FAA Etops Rule
Airbuba,
I have tried to look around and find something as you had requested, but I am not sure it's a final answer to your question.
Thanks, I saw that also, and the FAA ETOPS circular mentions a systems evaluation before going feet wet. Still, I wish the guidance were more clear if I someday find myself at the end of a long green table with no ashtray.