These days in fly by wire aircraft there is no such thing as manual flying. The computer flies the aircraft at all times and "manual" flight is still via the flight control computers, aka control wheel steering. The only time when you have to revert to real manual flying per se would be when a series of failures takes out all your flight computers.
Having said that, there is still a valid argument that pilots should master the skills of flying without the autopilot so to be ready for the occasion when the autopilot is not available.