I gave up and now work as a PA for a company director- I had some previous experience in recruitment and secretarial prior to flying and was lucky enough to be made permanaent after temping for a few months.
I can't say it compares with flying - I do miss the buzz and the people- but its great to be treated as something other than a number and not to have to stay awake for 36 hours on the trot...!
I'd say try temping to get a taste of what is available - its good for the CV and doesn't tie you down.