I have seen helos at The Headland Hotel at Newquay and also the Nare Hotel at St Mawes has a pad - both stunning and right on the coast.
There is a HLS in the BHAB handbook which is located at Hayle and Truro airfield may be available but is,
AFAIK, unlicensed.
Fuel wise, I am sure Avgas would be available at Lands End, Perranporth and Bodmin - Jet A1 from ?Lands End, Penzance Heliport and Newquay.
I would agree with the Scilly Isles. Just a short water crossing with excellent ATC both sides. The Islands are stunning, even in the winter and the gardens on Tresco are well worth a visit.