How would you know the automatics are in? If it's still flying when you get on the flight deck, they're in!
There was a Tristar whose crew accidentally switched off autopilot and did not notice - the plane entered a slow descent and eventually flew into a swamp. Can this happen with a 747?
Where's the transmit button? It's on the yolk. But it's not the first button you see, its on the front and the one you see first? Well, - that one's the autopilot disconnect!!!!!! There are up to two others depending on the customers specification, but they won't necessarily be obvious.
So, not all 747-400 cockpits are identical anyway... If you were to try and fly a plane where you are rated and current on the type, but unfamiliar with the airline (as, say, a passenger on industry discount) and neither of the pilots is in condition to give any briefing about airline and frame specifics, can you fly such a plane?