The only comment I've heard on this, in xx years flying, was a left-handed person on my flying course. He had had his pen pocket moved from his left sleeve to the right one, and he said it was much easier for him to write, as he did not have to take his (right) hand from the cyclic stick.
Speaking as a (mainly) right-handed person, I don't remember ever having any difficulty controlling the cyclic with my left hand. Very difficult to control the collective with the right hand, though.