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Old 22nd Dec 2022, 08:56
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slats11
 
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Interesting paper showing correlation between increased number of doses of vaccine and increased cases of C19 infection.

https://www.medrxiv.org/content/10.1...625v1.full.pdf

51,000 employees of Cleveland Clinic, so its not a small study.




Could be lots of reasons for this, and correlation in an observational study is not causation.

Maybe those most concerned about C19 are more likely to vax and also more likely to test themselves if any symptoms.
Or maybe older sicker are more likely to vax and more likely to come into contact with health system and be diagnosed with incidental infection - although in this study they were all employees of a health organisation and so they were all of working age and sufficiently well to be working.
Or maybe those who vax are higher risk (either older, or increased occupational risk) and thus really do get more infections (as above, this may be a significant factor in this particular study of working age people).
Or maybe vax does (somehow - ?? ADE) predispose you to infection.


Conversely, it seems quite likely that those people who avoided the vaccine had a higher risk tolerance - and hence may be more likely to acquire the infection. However the non-faxed had fewer infections.

The data is a mess and it’s very difficult to tease out.

However several studies from different countries have all found similar results over the past 12 months. More vaccine is associated (for whatever reason) with more infections.
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