The end of 747 production is rather bittersweet for me. I spent a good portion of my career working the 747, and my work on the 747-8/8F was probably the crowning achievement of that career.
It was more than a little frustrating to see the 747-8 be something less than successful (155 built). While I believe there is still a market for the 747-8F, that market is simply too limited to make continued production profitable.