Tribulations are common in the firm. Edward Augustus, fourth son of George III, was called upon to do his duty. He had to part ways with his lady of 27 years and contract a proper marriage to produce Victoria.
Biography ? EDWARD AUGUSTUS, Duke of KENT and STRATHEARN ? Volume V (1801-1820) ? Dictionary of Canadian Biography
I should also mention that Prince George performed his duty with Princess Charlotte and produced a daughter before they parted ways. Sadly the daughter and infant were both lost in childbirth, whereupon the younger brothers were called to duty for England and St. George.