Physical status of crew?
It seems that that PIA8303 is normally scheduled to depart Lahore at 10:00 local time. Based on the accident time, it is likely that the actual departure was delayed by about 3 hours. The cause of the delay may shed light on possible waiting conditions of the crew. At midday, the temperature in Lahore was 42C.
It will be interesting to eventually know if the accident investigation considers what time the flight crew actually showed up for duty and under what environmental conditions they waited for late departure. Could the pilots have been fatigued or otherwise impaired?
If the APU was not available due to unserviceability, company procedures for extended ground use, or insufficient fuel to accommodate extended APU use, the aircraft interior temperature could be very high with OAT of 42C or greater.