...But seriously, a re-engined VC10 with CFM56/V2500 engines, a glass cockpit, and maybe even FBW, would not offer anything better than the aforementioned A321XLR/Boeing 757...
Sure, it would have great short field performance, but I doubt it would cruise at anything like the speed of the original VC10...
And lastly...A QUIET VC10? are you mad?