Will there be pilotless commercial aircraft in the future? Almost certainly yes. When will large jet transports reach the equivalent of Level 5 autonomy? Hard to say but I’d put money on at least a decade or two.
AFAIK the technology has existed to do an auto-takeoff since at least the 1950s, so this particular demonstration is not that amazing, albeit it was using machine vision.
I’ll be more interested when they send an A350 solo, with instructions to do a couple of touch-and-goes, a PFL then come in flapless. Block the runway then see what it does...