The Americans don't really 'do' PICUS, so it is little understood, even by companies that should know like CREW.
All this having been said, I would actually call CREW and discuss the matter with them. Explain you do have the requirements on their website and are able to meet the JCAB regulations.
Of course, CREW may not want to put forward a candidate who is not as well qualified as other applicants and that is entirely their call. PARC will understand PICUS better (European) but they are a distinct second choice as their health insurance and loss of licence is nowhere as good as CREW.