Re A321 ops at SEN - The runway is 1850m TDA (which is not TORA, nor TODR)
An A321 cannot take off from Skiathos with a full load with the fuel needed to get back to UK - The JSI runway is 1630m TDA
They have to tech stop at anywhere as far up as Corfu - but often at nearer airports Volos Lemnos Kavala or SKG - sometimes with split pax loads.
The new A321 Neo at SEN it maybe possible to achieve the like of the Canaries and Corfu without the payload penalty of the current A320 and that is why SEN M.D has hinted they are doing £10m of works on the runway to enable the A321 to operate.
Remains to be seen on what route lengths they can achieve with SEN's runway re both Take-off's and landings using the much longer A321 and is the A321Neo the better option?
I am not sure if the new EZY A320Neo is still payload restricted to the Canaries as is their A320 CFM powered a/c.