Simple answer, if your young and single, go for it (Asia) . If you are older and have a family (or want one soon), don't do it to them. As a lot of expats find out, you can have 1000s of hours and check/training on a 777 or A330 and it counts for squat in the little sheltered workshop called Australia, there are always exceptions of course but by and large you will always end up starting at the bottom if/when you want to return.
My AUD2c/HKD$100