They don't cope well in high noise cockpits and the audio is fairly average in loud conditions. I have also found that when sitting next to someone with the EQ's, that if they are listening to music it will occasionally come over the intercom faintly. (quite annoying)
I had the BoseX's and they didn't cut the mustard up front of a radial powered aircraft and have now upgraded to the Zulu 2's. I found the mic much better with the Bose, but the Zulu's have better ANR in those sort of environments.
I don't think any of the big brands have wireless as of yet and personally I'd be a bit cautious using wireless headsets in commercial ops as you're bound to drop them, be it on the cockpit floor or worse, out the door when you (or a passenger) knocks them on the way out.