Ive gone short haul to long haul and it works much better for me and my family. When I was home very night, we worked such long and gruelling duties that I was a zombie anyhow and might as well have been anywhere but trying to continue my life.
Longhaul - The hardest part is staying awake at night two crew. The fact that I do one sector makes a huge difference. I can handle the Jet-lag at the moment.
Its a personal thing, the best you can hope for these days is the fortune to get into one of the better airlines and hang it out for the majority of your working life.
If i was doing it again (after 11 years) I would have attempted a different career and flown for pleasure as my previous job destroyed any love I had for flying. That said, my new job is restoring it and I feel like my old self again.
Do what you think you can put up with for 45+ years, it aint all about the money.