E145 is climbed using VS or FLC because that keeps you within modes that contain under & over speed protection. When I flew that machine, we were banned from using pitch because a crew one day made a mistake, and forgot that pitch does not afford such protection.
On my current type, we use pitch hold, because it's a docile machine to fly and pitch gives stable, repeatable results well within safety margins. We are banned from using VS in the climb, because of the possibility of commanding more than the aircraft is capable of giving, and there being no speed protection in such a mode.
Best advice, use either your operators, or the aircraft manufacturers guidance and try to understand the reasons behind their logic.
As has been said above, if the aircraft is incapable of going up, or staying up, then your likely pushing your luck.
And anyway, the big boys can tell you all about step-climbing!