Not from what I can see Poorjohn. There appear to be quite a few studies on the effects of Modafinil on military pilots, the results were generally very positive, so I can only assume that these findings are applied to Civil Aviation as well (please tell me if I'm wrong, I'm curious myself). Check the link below, its an abstract from a 2004 USAF study on F117 pilots after 37 hours sleep deprivation. The associated reading is quite cool, must have been a fun test.
Modafinil's effects on simulator per... [Aviat Space Environ Med. 2004] - PubMed - NCBI