M2D
A B747-400 at max take off weight (398tonnes) ex LHR would typically have a V1 ~ 155 kts, a Vr of about 170 and a V2 of 182 kts, so not dissimilar V1 speeds, but very different Vr and V2.
[I should add that this figures are for using reduced thrust and about 1.6 EPR on the RB211-524G engines where max thrust is about 1.72 EPR. Full thrust may result in an increased V1, I would guess].
This would suggest similar braking capabilities bearing in mind the differing TOWs involved. As to the relative brake unit weights I couldn't comment, nor therefore on the relative design pros and cons.
Numbers offered purely in response to your request.