There is a difference if you are "logging hours" in a 152 - if it's local flying, you aren't measuring productivity in terms of miles traveled. You probably fly at a fixed power setting, and the extra weight means your TAS is a percent or two low. Who cares? You log the hours - not the miles.
Transport flying is different: miles count! Extra fuel = extra weight = more power (thrust) to maintain Mach/TAS, thus higher fuel burn, and maybe you can't make the best cruise altitude when heavy. Big difference!