Sad to say, but full of freight does not mean that the flights are making money. There are lots of operators of both freighters and passenger aircraft in the world at the moment who are flying flat out full, but losing money. Unfortunately airline managers either choose to ignore this fact or hope that there are better times around the corner.
Scottie from Star Trek famously said "ye canna change the laws of physics"
I say " ye canna change the laws of economics"