For up to four seat touring, the Twin Comm wins hands down.
While I would generally agree with your sentiments DFC (and I wouldn't swap our Twin Com for anything else), most Twin Coms with reasonable kit are not capable of carrying 4 normal adults on a typical tour. With 4 adults plus light baggage and a dinghy, you're down to about 3 hours to dry tanks. Factoring in IFR reserves and the odd alternate that's 45 mins away, that doesn't give much flexibility.
If you're regularly flying 4-up, go for something with a higher load capability.