Well I was trying to keep out of this, but I cannot take any more.
There MUST be more chance of AN engine failure on a 4 engined aircraft, than a 2 engined aircraft, PARTICULARLY if they have the same engine type.
Okay, on a 4 you have 3 left, where on a 2 you are down to only 1.
NOT saying which is safer, or which I prefer, but there MUST be more chance of AN engine failure on a 4 engined aircraft than a 2.
There would be much LESS chance of losing ALL engines on a 4, as compared to the 2 on a twin, but MORE chance of losing AN engine.
To me it is a matter of the odds.
IF you had say 400 pax on one aircraft, and 200 pax on another aircraft, (assuming there were all in similar condition, like the engines are in similar condition to each other) the odds of ONE passenger having say a heart attack would be greater on the aircraft with 400 pax, however the odds of EVERY pax having a heart attack would be less on the one with 400 pax.